All Publications

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  1. Han S, Dicker ML, Lopez-Ichikawa M, Vu NK, Rubinsky B, Chang TT. Irreversible Electroporation of the Liver Increases the Transplant Engraftment of Hepatocytes. J Surg Res. 2023 Sep 20; 293:128-135. View in PubMed
  2. Nastase G, Botea F, Be?chea GA, Câmpean ?I, Barcu A, Neac?u I, Herlea V, Popescu I, Chang TT, Rubinsky B, ?erban A. Isochoric Supercooling Organ Preservation System. Bioengineering (Basel). 2023 Aug 07; 10(8). View in PubMed
  3. Botea F, Nastase G, Herlea V, Chang TT, ?erban A, Barcu A, Rubinsky B, Popescu I. An exploratory study on isochoric supercooling preservation of the pig liver. Biochem Biophys Rep. 2023 Jul; 34:101485. View in PubMed
  4. Zhang Y, Lv Y, Wang Y, Chang TT, Rubinsky B. Pancreatic islets implanted in an irreversible electroporation generated extracellular matrix in the liver. Radiol Oncol. 2023 03 01; 57(1):51-58. View in PubMed
  5. Weng Y, Han S, Sekyi MT, Su T, Mattis AN, Chang TT. Self-Assembled Matrigel-Free iPSC-Derived Liver Organoids Demonstrate Wide-Ranging Highly Differentiated Liver Functions. Stem Cells. 2023 03 02; 41(2):126-139. View in PubMed
  6. Yun Weng, Simon Han, Maria T Sekyi, Tao Su, Aras N Mattis, Tammy T Chang. Self-assembled Matrigel-free iPSC-derived liver organoids demonstrate wide-ranging highly-differentiated liver functions. Stem Cells. 2022. View in PubMed
  7. Lopez-Ichikawa M, Vu NK, Nijagal A, Rubinsky B, Chang TT. Neutrophils are important for the development of pro-reparative macrophages after irreversible electroporation of the liver in mice. Sci Rep. 2021 07 22; 11(1):14986. View in PubMed
  8. Song X, Xu H, Wang P, Wang J, Affo S, Wang H, Xu M, Liang B, Che L, Qiu W, Schwabe RF, Chang TT, Vogl M, Pes GM, Ribback S, Evert M, Chen X, Calvisi DF. Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation. J Hepatol. 2021 10; 75(4):888-899. View in PubMed
  9. Weng Y, Lieberthal TJ, Zhou VX, Lopez-Ichikawa M, Armas-Phan M, Bond TK, Yoshida MC, Choi WT, Chang TT. Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling. JCI Insight. 2020 10 15; 5(20). View in PubMed
  10. Conroy PC, Colley A, Bongiovanni T, Chang TT, Harris H. Jejunal prolapse and incarceration following feeding tube exchange. J Trauma Acute Care Surg. 2020 12; 89(6):e175-e176. View in PubMed
  11. Maya A. Lopez-Ichikawa, Tammy T. Chang. Intra-Vital Imaging Demonstrates Robust Recruitment of Neutrophils after Irreversible Electroporation Tissue Ablation. Journal of the American College of Surgeons. 2019 Oct 1; 229(4):e117-e118. View in PubMed
  12. Maya A. Lopez-Ichikawa,Tammy T. Chang. Intra-Vital Imaging Demonstrates Robust Recruitment of Neutrophils after Irreversible Electroporation Tissue Ablation. . 2019 Oct 1; 229(4):e117-e118. View in PubMed
  13. Lyu C, Lopez-Ichikawa M, Rubinsky B, Chang TT. Normal and fibrotic liver parenchyma respond differently to irreversible electroporation. HPB (Oxford). 2019 10; 21(10):1344-1353. View in PubMed
  14. Jennifer Y. Chen, Dhruv Thakar, Tammy T. Chang. Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment. . 2019 Jan 1; 387-417. View in PubMed
  15. Jennifer Y. Chen, Dhruv Thakar, Tammy T. Chang. Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment. Fibrosis in Disease. 2019 Jan 1; 387-417. View in PubMed
  16. Zhang Y, Lyu C, Liu Y, Lv Y, Chang TT, Rubinsky B. Molecular and histological study on the effects of non-thermal irreversible electroporation on the liver. Biochem Biophys Res Commun. 2018 06 07; 500(3):665-670. View in PubMed
  17. Chang TT, Zhou VX, Rubinsky B. Using non-thermal irreversible electroporation to create an in vivo niche for exogenous cell engraftment. BioTechniques. 2017; 62:229-231. View in PubMed
  18. Chang TT, Zhou VX, Rubinsky B. Using non-thermal irreversible electroporation to create an in vivo niche for exogenous cell engraftment. Biotechniques. 2017 05 01; 62(5):229-231. View in PubMed
  19. Chang TT. Reply. Hepatology. 2017 05; 65(5):1781-1782. View in PubMed
  20. Zhou VX, Lolas M, Chang TT. Direct orthotopic implantation of hepatic organoids. J Surg Res. 2017 05 01; 211:251-260. View in PubMed
  21. Chang TT, Thakar D, Weaver VM. Force-dependent breaching of the basement membrane. Matrix Biol. 2017 01; 57-58:178-189. View in PubMed
  22. Tammy T. Chang, Vivian X. Zhou. Hepatic Focal Adhesion Kinase Signaling Modulates Development of Liver Fibrosis. Journal of the American College of Surgeons. 2016 Oct 1; 223(4):e25. View in PubMed
  23. Tammy T. Chang,Vivian X. Zhou. Hepatic Focal Adhesion Kinase Signaling Modulates Development of Liver Fibrosis. . 2016 Oct 1; 223(4):e25. View in PubMed
  24. Choi WT, Chang TT, Gill RM. Gastrointestinal Zygomycosis Masquerading as Acute Appendicitis. Case Rep Gastroenterol. 2016 Jan-Apr; 10(1):81-7. View in PubMed
  25. Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha. Hepatology. 2016 07; 64(1):261-75. View in PubMed
  26. Hughes-Fulford M, Chang TT, Martinez EM, Li CF. Spaceflight alters expression of microRNA during T-cell activation. FASEB J. 2015 Dec; 29(12):4893-900. View in PubMed
  27. Chang TT, Spurlock SM, Candelario TL, Grenon SM, Hughes-Fulford M. Spaceflight impairs antigen-specific tolerance induction in vivo and increases inflammatory cytokines. FASEB J. 2015 Oct; 29(10):4122-32. View in PubMed
  28. Chang TT, Hughes-Fulford M. Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregates. Biomaterials. 2014 Feb; 35(7):2162-71. View in PubMed
  29. Chang TT, Walther I, Li CF, Boonyaratanakornkit J, Galleri G, Meloni MA, Pippia P, Cogoli A, Hughes-Fulford M. The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity. J Leukoc Biol. 2012 Dec; 92(6):1133-45. View in PubMed
  30. Chang TT, Hughes-Fulford M. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes. Tissue Eng Part A. 2009 Mar; 15(3):559-67. View in PubMed
  31. Chang TT, Corvera CU. Caudate split for open and laparoscopic liver resections. J Am Coll Surg. 2008 Dec; 207(6):e7-9. View in PubMed
  32. Chang TT, Sawhney R, Monto A, Davoren JB, Kirkland JG, Stewart L, Corvera CU. Implementation of a multidisciplinary treatment team for hepatocellular cancer at a Veterans Affairs Medical Center improves survival. HPB (Oxford). 2008; 10(6):405-11. View in PubMed
  33. Chang TT, Schecter WP. Injury in the elderly and end-of-life decisions. Surg Clin North Am. 2007 Feb; 87(1):229-45, viii. View in PubMed
  34. Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. Eur J Immunol. 2003 Jul; 33(7):2022-2032. View in PubMed
  35. Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. Eur J Immunol. 2002 Sep; 32(9):2687-97. View in PubMed
  36. Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, Berry G, DeKruyff RH, Umetsu DT. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med. 2002 Sep; 8(9):1024-32. View in PubMed
  37. Chang TT, Kuchroo VK, Sharpe AH. Role of the B7-CD28/CTLA-4 pathway in autoimmune disease. Curr Dir Autoimmun. 2002; 5:113-30. View in PubMed