Chang Lab for Liver Tissue Engineering - Homepage
Translating Regenerative Surgery on the Liver From Concept to Therapeutic Reality
Tissue engineering and regeneration are the next evolutionary step in surgical practice. As surgeons, we resect, reconstruct, and transplant to treat a diverse array of diseases resulting from acute inflammation, congenital malformation, malignancy, or organ failure. In the near future, our armamentarium will increase to include using our surgical skills to induce tissue regeneration in situ or to implant ex vivo engineered organs. Accelerating advances in biotechnology, stem cell biology, and minimally invasive surgery are ripe for convergence, which will lead to the creation of novel surgical treatments to replace diseased or dysfunctional tissues. Our lab's goal is to make significant contributions to bringing these regenerative surgical therapies from the lab into the operating room.